Quantitative Systems Pharmacology Model for Alzheimer Disease Indicates Targeting Sphingolipid Dysregulation as Potential Treatment Option
Author:
Affiliation:
1. AbbVie Deutschland GmbH & Co. KG; Ludwigshafen Germany
2. Certara QSP; Innovation centre; Unit 43; Canterbury UK
3. AbbVie Inc.; North Chicago Illinois USA
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/psp4.12351/fullpdf
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3. The rise of systems pharmacology in drug discovery and development;Benson;Future Med. Chem.,2014
4. Systems pharmacology: bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development;Graaf;Pharm. Res.,2011
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