A Comprehensive Framework for Physiologically‐Based Pharmacokinetic Modeling in Matlab

Author:

Stader Felix123,Penny Melissa A.23,Siccardi Marco4,Marzolini Catia13

Affiliation:

1. Division of Infectious Diseases and Hospital EpidemiologyDepartments of Medicine and Clinical ResearchUniversity Hospital Basel Basel Switzerland

2. Infectious Disease Modelling UnitDepartment of Epidemiology and Public HealthSwiss Tropical and Public Health Institute Basel Switzerland

3. University of Basel Basel Switzerland

4. Department of Molecular and Clinical PharmacologyInstitute of Translational MedicineUniversity of Liverpool Liverpool UK

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Reference62 articles.

1. Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance

2. U.S. Food and Drug Administration.Physiologically based pharmacokinetic analysis – format and content. Guidance for industry (2016). Accessed January 2 2018.

3. European Medicines Agency.Guideline on the qualification and reporting of physiologically based pharmacokinetic (PBPK) modelling and simulation (2016). Accessed January 2 2018.

4. Predicting drug–drug interactions: application of physiologically based pharmacokinetic models under a systems biology approach

5. Physiology-Based Pharmacokinetics of Caspofungin for Adults and Paediatrics

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