A nationwide, population‐based study on specialized care for acute heart failure throughout the COVID‐19 pandemic

Author:

Cannata Antonio12ORCID,Mizani Mehrdad A.3,Bromage Daniel I.12,Piper Susan E.12,Hardman Suzanna M.C.4,Sudlow Cathie3,de Belder Mark5,Deanfield John5,Gardner Roy S.67,Clark Andrew L.8,Cleland John G.F.9,McDonagh Theresa A.12,

Affiliation:

1. British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine, Faculty of Life Science King's College London London UK

2. Cardiology Department King's College Hospital NHS Foundation Trust London UK

3. British Heart Foundation Data Science Centre Health Data Research UK London UK

4. Whittington Health London UK

5. National Institute for Cardiovascular Outcomes Research (NICOR) NHS Arden and Greater East Midlands Commissioning Support Unit Leicester UK

6. BHF Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences University of Glasgow Glasgow UK

7. Scottish National Advanced Heart Failure Service Golden Jubilee National Hospital Clydebank UK

8. Hull University Teaching Hospitals Trust Hull UK

9. British Heart Foundation Centre of Research Excellence, School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK

Abstract

AbstractAimsThe COVID‐19 pandemic disrupted the delivery of care for patients with heart failure (HF), leading to fewer HF hospitalizations and increased mortality. However, nationwide data on quality of care and long‐term outcomes across the pandemic are scarce.Methods and resultsWe used data from the National Heart Failure Audit (NHFA) linked to national records for hospitalization and deaths. We compared pre‐COVID (2018–2019), COVID (2020), and late/post‐COVID (2021–2022) periods. Data for 227 250 patients admitted to hospital with HF were analysed and grouped according to the admission year and the presence of HF with (HFrEF) or without reduced ejection fraction (non‐HFrEF). The median age at admission was 81 years (interquartile range 72–88), 55% were men (n = 125 975), 87% were of white ethnicity (n = 102 805), and 51% had HFrEF (n = 116 990). In‐hospital management and specialized cardiology care were maintained throughout the pandemic with an increasing percentage of patients discharged on disease‐modifying medications over time (p < 0.001). Long‐term outcomes improved over time (hazard ratio [HR] 0.92, 95% confidence interval [CI] 0.90–0.95, p < 0.001), mainly driven by a reduction in cardiovascular death. Receiving specialized cardiology care was associated with better long‐term outcomes both for those who had HFrEF (HR 0.79, 95% CI 0.77–0.82, p < 0.001) and for those who had non‐HFrEF (HR 0.87, 95% CI 0.85–0.90, p < 0.001).ConclusionsDespite the disruption of healthcare systems, the clinical characteristics of patients admitted with HF were similar and the overall standard of care was maintained throughout the pandemic. Long‐term survival of patients hospitalized with HF continued to improve after COVID‐19, especially for HFrEF.

Funder

British Heart Foundation

Medical Research Council

Publisher

Wiley

Reference33 articles.

1. National Institute for Cardiovascular Outcomes Research (NICOR).National Heart Failure Audit 2019 Summary Report2019.https://www.hqip.org.uk/wp‐content/uploads/2019/09/Ref‐129‐Cardiac‐Heart‐Failure‐Summary‐Report‐2019‐FINAL.pdf(2 May 2024).

2. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

3. Impact of the COVID-19 pandemic on in-hospital mortality in cardiovascular disease: a meta-analysis

4. Potential Effects of Coronaviruses on the Cardiovascular System

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