Spindle cell squamous cell carcinoma of the maxillary sinus as a metachronous head and neck cancer

Author:

Shima Kaori1ORCID,Shimojukkoku Yudai12,Hijioka Hiroshi3ORCID,Ishihata Kiyohide2ORCID,Sasahira Tomonori1ORCID

Affiliation:

1. Department of Molecular Oral Pathology and Oncology Kagoshima University Graduate School of Medical and Dental Sciences Japan

2. Department of Maxillofacial Diagnostic and Surgical Sciences Kagoshima University Graduate School of Medical and Dental Sciences Japan

3. Department of Oral and Maxillofacial Surgery Kagoshima University Hospital Japan

Abstract

AbstractBackgroundSpindle cell squamous cell carcinoma (SpSCC) is a rare subtype of squamous cell carcinoma (SCC) showing an unfavorable prognosis. Histologically, SpSCC shows biphasic proliferation of spindle cells and nests of SCC.Case presentationAn 85‐year‐old Japanese man with a medical history of oral SCC three years ago had SpSCC of the right maxillary sinus. The tumor showed aggressive proliferation of spindle cells with nests of conventional SCC. Subsequent lymph node metastases revealed findings of conventional SCC.ConclusionThis case report contributes to the accumulation of a rare subtype of SCC and multiple cancers of the head and neck region.

Publisher

Wiley

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