Design, synthesis, biological evaluation, and in silico studies of 2‐aminobenzothiazole derivatives as potent PI3Kα inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, biological evaluation, and in silico studies of 2‐aminobenzothiazole derivatives as potent PI3Kα inhibitors

Published:2022-06-03 Issue:10 Volume:355 Page:2200146
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Archiv der Pharmazie

Author:

Haider Kashif¹^ORCID,Ahmad Kamal¹,Najmi Abul Kalam²,Das Subham³,Joseph Alex³,Shahar Yar M.¹⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry School of Pharmaceutical Education & Research Jamia Hamdard India

2. Department of Pharmacology School of Pharmaceutical Education and Research Jamia Hamdard India

3. Department of Pharmaceutical Chemistry Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education Manipal India

4. Centre for Excellence for Biomaterials Engineering, Faculty of Applied Sciences. AIMST Bedong Malaysia

Funder

Indian Council of Medical Research

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ardp.202200146

Reference32 articles.

1. Synthetic lethality on drug discovery: an update on cancer therapy

2. Breast and Ovarian Cancer

3. Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials

4. Design Synthesis and Biological Evaluation of Dithiocarbamate Substituted 2-Aminobenzothiazole Derivatives as Proviral Integration Site of Moloney Murine Leukaemia Virus 1 Kinase Inhibitors

5. Advances in 2‐substituted benzothiazole scaffold‐based chemotherapeutic agents

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1. Synthesis, characterization, antimicrobial screening and in-silico studies of thiadiazole derivatives;Journal of Molecular Structure;2024-11

2. Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents;Scientific Reports;2024-04-11

3. Computational-guided approach for identification of PI3K alpha inhibitor in the treatment of hepatocellular carcinoma by virtual screening and water map analysis;Journal of Biomolecular Structure and Dynamics;2024-01-10

4. Identification of natural product as selective PI3Kα inhibitor against NSCLC: multi-ligand pharmacophore modeling, molecular docking, ADME, DFT, and MD simulations;Molecular Diversity;2023-09-15

5. 2-Aminobenzothiazoles in anticancer drug design and discovery;Bioorganic Chemistry;2023-06

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