Affiliation:
1. School of Chemistry and Environmental Engineering Wuhan Institute of Technology Wuhan 430205 P. R. China
2. School of Chemistry and Chemical Engineering Henan Normal University Xinxiang 453007 P. R. China
3. Key Laboratory of Green Chemical Process Ministry of Education Wuhan Institute of Technology Wuhan 430205 P. R. China
Abstract
AbstractA copper‐catalyzed efficient synthesis of alkynyl thioamides starting from tetraalkyl thiuram compounds (TMTM: tetramethyl thiuram monosulfide, TIBTM: tetraisobutyl thiuram monosulfide) and alkynes was reported. Thus, tetraalkyl thiurams reacted with alkynes smoothly, giving a variety of alkynyl thioamides promoted by CuI/Cs2CO3 system. This protocol features easy operation, inexpensive starting materials and good yields, illustrating its potential synthetic value for the synthesis of thioamides and their derivatives.
Funder
Henan Normal University
State Key Laboratory of Environmental Chemistry and Ecotoxicology
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences
Ministry of Higher Education and Scientific Research
Wuhan Institute of Technology
Subject
Organic Chemistry,Physical and Theoretical Chemistry