Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases-Reference-Cited by-同舟云学术

Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases

Published:2024-08 Issue:8 Volume:13 Page:
ISSN:2001-3078
Container-title:Journal of Extracellular Vesicles
language:en
Short-container-title:J of Extracellular Vesicle

Author:

Pinheiro Ana Acacia Sá¹²^ORCID,Torrecilhas Ana Claudia³^ORCID,Souza Bruno Solano de Freitas⁴⁵^ORCID,Cruz Fernanda Ferreira¹²^ORCID,Guedes Herbert Leonel de Matos⁶⁷^ORCID,Ramos Tadeu Diniz⁶⁷^ORCID,Lopes‐Pacheco Miqueias¹⁸^ORCID,Caruso‐Neves Celso¹²⁹^ORCID,Rocco Patricia R. M.¹²⁹^ORCID

Affiliation:

1. Instituto de Biofísica Carlos Chagas Filho Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil

2. Rio de Janeiro Innovation Network in Nanosystems for Health‐NanoSAÚDE/Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) Rio de Janeiro Brazil

3. Departamento de Ciências Farmacêuticas Diadema Campus, Instituto de Ciências Ambientais, Químicas e Farmacêuticas Universidade Federal de São Paulo (UNIFESP) Diadema São Paulo Brazil

4. Center for Biotechnology and Cell Therapy São Rafael Hospital Salvador Brazil

5. D'Or Institute for Research and Education (IDOR) Salvador Brazil

6. Instituto de Microbiologia Paulo de Goés (IMPG) Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro Brazil

7. Fundação Oswaldo Cruz (FIOCRUZ) Instituto Oswaldo Cruz (IOC) Rio de Janeiro Brazil

8. Deparment of Pediatrics Center for Cystic Fibrosis and Airway Disease Research Emory University School of Medicine Atlanta Georgia USA

9. National Institute of Science and Technology for Regenerative Medicine INCT‐REGENERA Rio de Janeiro Brazil

Abstract

AbstractParasitic diseases have a significant impact on human and animal health, representing a major hazard to the public and causing economic and health damage worldwide. Extracellular vesicles (EVs) have long been recognized as diagnostic and therapeutic tools but are now also known to be implicated in the natural history of parasitic diseases and host immune response modulation. Studies have shown that EVs play a role in parasitic disease development by interacting with parasites and communicating with other types of cells. This review highlights the most recent research on EVs and their role in several aspects of parasite‐host interactions in five key parasitic diseases: Chagas disease, malaria, toxoplasmosis, leishmaniasis and helminthiases. We also discuss the potential use of EVs as diagnostic tools or treatment options for these infectious diseases.

Publisher

Wiley

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