Mid‐life adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and late‐life subjective cognitive complaints in women

Author:

Song Yixiao12,Wu Fen1,Sharma Sneha3,Clendenen Tess V.1,India‐Aldana Sandra1,Afanasyeva Yelena1,Gu Yian45,Koenig Karen L.1,Zeleniuch‐Jacquotte Anne1,Chen Yu16

Affiliation:

1. Division of Epidemiology Department of Population Health NYU Grossman School of Medicine New York New York USA

2. Department of Epidemiology NYU School of Global Public Health New York New York USA

3. NYU Grossman School of Medicine New York New York USA

4. Department of Neurology Columbia University New York New York USA

5. Taub Institute for Research in Alzheimer's Disease and the Aging Brain Columbia University New York New York USA

6. Department of Environmental Medicine NYU Grossman School of Medicine New York New York USA

Abstract

AbstractINTRODUCTIONEvidence is limited on the role of mid‐life Dietary Approaches to Stop Hypertension (DASH) diet in late‐life subjective cognitive complaints (SCCs).METHODSWe included 5116 women (mean age in 1985–1991: 46 years) from the New York University Women's Health Study. SCCs were assessed from 2018 to 2020 (mean age: 79 years) by a 6‐item questionnaire.RESULTSCompared to women in the bottom quartile of the DASH scores, the odds ratio (OR) for having two or more SCCs was 0.83 (95% confidence interval: 0.70–0.99) for women in the top quartile of DASH scores at baseline (P for trend = 0.019). The association was similar with multiple imputation and inverse probability weighting to account for potential selection bias. The inverse association was stronger in women without a history of cancer (P for interaction = 0.003).DISCUSSIONGreater adherence to the DASH diet in mid‐life was associated with lower prevalence of late‐life SCCs in women.

Funder

National Institutes of Health

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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