Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma

Author:

Zuleger Cindy L.12,Kang Chulhi1,Ranheim Erik A.13,Kurzman Ilene D.4,Macklin Michael D.12,Newton Michael A.15,Wolchok Jedd D.6,Vail David M.14,Eriksson Elof7,Albertini Mark R.128ORCID

Affiliation:

1. University of Wisconsin Carbone Cancer Center; Madison Wisconsin USA

2. Department of Medicine; University of Wisconsin School of Medicine and Public Health; Madison Wisconsin USA

3. Department of Pathology; University of Wisconsin School of Medicine and Public Health; Madison Wisconsin USA

4. Department of Medical Sciences; University of Wisconsin School of Veterinary Medicine; Madison Wisconsin USA

5. Department of Biostatistics and Medical Informatics; University of Wisconsin School of Medicine and Public Health; Madison Wisconsin USA

6. Memorial Sloan Kettering Cancer Center; New York USA

7. Division of Plastic Surgery; Brigham and Women's Hospital; Harvard Medical School; Boston Massachusetts USA

8. Medical Service; William S. Middleton Memorial Veterans Hospital; Madison Wisconsin USA

Funder

National Center for Advancing Translational Sciences

National Cancer Institute

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

Wiley

Subject

General Veterinary

Reference44 articles.

1. Development of an allogeneic whole-cell tumor vaccine expressing xenogeneic gp100 and its implementation in a phase II clinical trial in canine patients with malignant melanoma;Alexander;Cancer Immunology, Immunotherapy,2006

2. Optimization of intradermal vaccination by DNA tattooing in human skin;Berg;Human Gene Therapy,2009

3. Long-term survival of dogs with advanced malignant melanoma after DNA vaccination with xenogeneic human tyrosinase: a phase I trial;Bergman;Clinical Cancer Research,2003

4. A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression;Bins;Nature Medicine,2005

5. ClinicalTrials.gov 2016 A service of the U.S. National Institutes of Health https://clinicaltrials.gov/

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