Multiple myeloma in the mandible mimicking a radicular cyst: A case report and literature review

Author:

Shimada Yasuyuki1ORCID,Miyazaki Hideki2,Hangaishi Akira3,Maruoka Yutaka14

Affiliation:

1. Department of Oral and Maxillofacial Surgery National Center for Global Health and Medicine Shinjuku‐ku Tokyo Japan

2. Department of Pathology National Center for Global Health and Medicine Shinjuku‐ku Tokyo Japan

3. Department of Hematology National Center for Global Health and Medicine Shinjuku‐ku Tokyo Japan

4. Department of Oral and Maxillofacial Surgical Oncology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Bunkyo‐ku Tokyo Japan

Abstract

AbstractBackgroundMultiple myeloma (MM) is a hematopoietic malignancy characterized by monoclonal plasma cell proliferation. Mandibular involvement in patients with MM is rare, and its clinical and radiological characteristics remain unclear.Case PresentationA 78‐year‐old man presented with MM in the mandible, mimicking a radicular cyst. Chemotherapy yielded a poor prognosis, and the patient died 1.5 years post‐diagnosis. Literature suggests that jawbone involvement of MM is a poor prognostic factor.ConclusionThis report highlights the features of MM in the jawbone, and its variable manifestation, which may include non‐neoplastic findings, thus emphasizing the importance of a definitive biopsy‐based diagnosis.

Publisher

Wiley

Subject

Otorhinolaryngology

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