Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice

Author:

Slijepcevic Davor1,Roscam Abbing Reinout L.P.1,Katafuchi Takeshi2,Blank Antje34ORCID,Donkers Joanne M.1,van Hoppe Stéphanie5,de Waart Dirk. R.1,Tolenaars Dagmar1,van der Meer Jonathan H.M.1,Wildenberg Manon16,Beuers Ulrich16,Oude Elferink Ronald P.J.16,Schinkel Alfred H.5,van de Graaf Stan F.J.16ORCID

Affiliation:

1. Tytgat Institute for Liver and Intestinal ResearchAcademic Medical CenterAmsterdam The Netherlands

2. University of Texas Southwestern Medical CenterDallas TX

3. Department of Clinical Pharmacology and PharmacoepidemiologyHeidelberg University HospitalHeidelberg Germany

4. German Center for Infection Research (DZIF)Heidelberg Partner SiteHeidelberg Germany

5. Division of Molecular Oncologythe Netherlands Cancer InstituteAmsterdam The Netherlands

6. Department of Gastroenterology and HepatologyAcademic Medical CenterAmsterdam The Netherlands

Funder

European Research Council

Publisher

Wiley

Subject

Hepatology

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