Proposal of a Safe and Effective Study Design for CYP3A‐Mediated Drug‐Drug Interactions-Reference-Cited by-同舟云学术

Proposal of a Safe and Effective Study Design for CYP3A‐Mediated Drug‐Drug Interactions

Published:2020-05-21 Issue:10 Volume:60 Page:1294-1303
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Rohr Brit Silja¹,Mikus Gerd¹^ORCID

Affiliation:

1. Department of Clinical Pharmacology and Pharmacoepidemiology University of Heidelberg Heidelberg Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1622

Reference37 articles.

1. FDA.Clinical drug interaction studies—study design data analysis and clinical implications. Guidance for Industry.https://www.fda.gov/media/134581/download. Accessed January 24 2020.

2. No Increased Risk of Ketoconazole Toxicity in Drug-Drug Interaction Studies

3. Ketoconazole and Liver Injury: A Five-Year Update

4. Ritonavir is the best alternative to ketoconazole as an index inhibitor of cytochrome P450-3A in drug-drug interaction studies

5. Determining the Time Course of CYP3A Inhibition by Potent Reversible and Irreversible CYP3A Inhibitors Using A Limited Sampling Strategy

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