Non‐psychotropic <i>Cannabis sativa</i> L. phytocomplex modulates microglial inflammatory response through <scp>CB2</scp> receptors‐, endocannabinoids‐, and <scp>NF‐κB</scp> ‐mediated signaling-Reference-Cited by-同舟云学术

Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB ‐mediated signaling

Published:2022-04-08 Issue:5 Volume:36 Page:2246-2263
ISSN:0951-418X
Container-title:Phytotherapy Research
language:en
Short-container-title:Phytotherapy Research

Author:

Borgonetti Vittoria¹^ORCID,Benatti Cristina²³^ORCID,Governa Paolo⁴^ORCID,Isoldi Giovanni⁵,Pellati Federica³^ORCID,Alboni Silvia²³^ORCID,Tascedda Fabio²³⁶^ORCID,Montopoli Monica⁷^ORCID,Galeotti Nicoletta¹^ORCID,Manetti Fabrizio⁴^ORCID,Miraldi Elisabetta⁸,Biagi Marco⁸^ORCID,Rigillo Giovanna³^ORCID

Affiliation:

1. Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology University of Florence Florence Italy

2. Center for Neuroscience and Neurotechnology University of Modena and Reggio Emilia Modena Italy

3. Department of Life Sciences University of Modena and Reggio Emilia Modena Italy

4. Department of Biotechnology, Chemistry and Pharmacy (Department of Excellence 2018‐2022) University of Siena Siena Italy

5. Materia Medica Processing S.r.l. Siena Italy

6. Consorzio Interuniversitario Biotecnologie Trieste Italy

7. Department of Pharmaceutical and Pharmacological Sciences University of Padua Padua Italy

8. Department of Physical Sciences, Earth and Environment University of Siena Siena Italy

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.7458

Reference95 articles.

1. Anti-inflammatory activity of cannabinoid receptor 2 ligands in primary hPDL fibroblasts

2. Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer

3. Interleukin 18 activates MAPKs and STAT3 but not NF-κB in hippocampal HT-22 cells

4. Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy

5. Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages

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