Improved survival with enasidenib versus standard of care in relapsed/refractory acute myeloid leukemia associated with IDH2 mutations using historical data and propensity score matching analysis

Author:

Botton Stéphane1ORCID,Brandwein Joseph M.2ORCID,Wei Andrew H.3,Pigneux Arnaud4,Quesnel Bruno5,Thomas Xavier6,Legrand Ollivier7,Recher Christian8,Chantepie Sylvain9,Hunault‐Berger Mathilde10,Boissel Nicolas11,Nehme Salem A.12,Frattini Mark G.13,Tosolini Alessandra13,Marion‐Gallois Roland13,Wang Jixian J.13,Cameron Chris14,Siddiqui Muhaimen14,Hutton Brian15,Milkovich Gary16,Stein Eytan M.17

Affiliation:

1. Departement d'hematologie Institut Gustave Roussy Villejuif France

2. University of Alberta Edmonton Alberta Canada

3. Alfred Hospital and Monash University Melbourne Australia

4. CHU Bordeaux Hôpital du Haut Lévêque Bordeaux France

5. CHU Lille Lille France

6. Centre Hospitalier Lyon Sud Pierre Bénite France

7. APHP Hôpital Saint‐Antoine Paris France

8. CHU de Toulouse Université de Toulouse III Paul Sabatier Toulouse France

9. CHU de Caen Caen France

10. CHU Angers Angers France

11. Hôpital Saint‐Louis Paris France

12. Celgene International, a Bristol Myers Squibb Company Boudry Switzerland

13. Bristol Myers Squibb Summit New Jersey USA

14. Cornerstone Research Group Burlington Ontario Canada

15. Ottawa Hospital Research Institute Ottawa Ontario Canada

16. RJM Group LLC Crown Point Indiana USA

17. Memorial Sloan Kettering Cancer Center New York New York USA

Funder

Bristol-Myers Squibb

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference35 articles.

1. Acute Myeloid Leukemia

2. ‘Acute myeloid leukemia: a comprehensive review and 2016 update’

3. Systematic Literature Review of the Global Incidence and Prevalence of Myelodysplastic Syndrome and Acute Myeloid Leukemia

4. Considerations and challenges for patients with refractory and relapsed acute myeloid leukaemia

5. Cancer Research UK.Acute myeloid leukaemia (AML) incidence statistics.2015. Accessed May 2018.http://www.cancerresearchuk.org/health‐professional/cancer‐statistics/statistics‐by‐cancer‐type/leukaemia‐aml/incidence

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