Obestatin controls the ubiquitin-proteasome and autophagy-lysosome systems in glucocorticoid-induced muscle cell atrophy

Author:

Cid-Díaz Tania1,Santos-Zas Icía1,González-Sánchez Jessica1,Gurriarán-Rodríguez Uxía2,Mosteiro Carlos S.1,Casabiell Xesús3,García-Caballero Tomás4,Mouly Vincent5,Pazos Yolanda1,Camiña Jesús P.1

Affiliation:

1. Área de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago (IDIS); Complejo Hospitalario Universitario de Santiago (CHUS), Servicio Gallego de Salud (SERGAS); Choupana s/n 15706 Santiago de Compostela Spain

2. Sprott Center for Stem Cell Research; Ottawa Hospital Research Institute; 501 Smyth Road Ottawa Ontario K1H 8L6 Canada

3. Departamento de Fisiología; Facultad de Veterinaria, Universidad de Santiago de Compostela (USC); Carballo Calero s/n 27002 Lugo Spain

4. Departamento de Ciencias Morfológicas; Facultad de Medicina, USC; San Francisco s/n 15704 Santiago de Compostela Spain

5. Sorbonne Universités, UPMC Université Paris 06, INSERM UMRS974, CNRS FRE3617, Center for Research in Myology; 47 Boulevard de l'hôpital 75013 Paris France

Funder

IDIS

Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia

Instituto de Salud Carlos III

Federación Española de Enfermedades Raras

Publisher

Wiley

Subject

Physiology (medical),Orthopedics and Sports Medicine

Reference68 articles.

1. Balancing muscle hypertrophy and atrophy;Hoffman;Nat Med,2004

2. Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1;Bodine;Am J Physiol Endocrinol Metab,2014

3. Cellular mechanisms regulating protein synthesis and skeletal muscle hypertrophy in animals;Miyazaki;J Appl Physiol,2009

4. mTOR signaling in growth control and disease;Laplante;Cell,2012

5. Signaling in muscle atrophy and hypertrophy;Sandri;Physiology (Bethesda),2008

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