Psychedelic‐assisted therapy for palliative care within a home treatment setting: A case report

Author:

Federico Seragnoli12ORCID,Geo Martignoni3,Entela Martignoni3,Bachmann Silke14ORCID,Elisa Rabitti5ORCID,Silvio Cavuto6ORCID,Zoë Dubus7,Louise Penzenstadler1,Gabriel Thorens1,Joël Billieux2ORCID,Daniele Zullino18

Affiliation:

1. Psychiatry Department Geneva University Hospitals Geneva Switzerland

2. Institute of Psychology University of Lausanne Lausanne Switzerland

3. Private practice Gordola, Ticino Switzerland

4. Department of Psychiatry University Hospitals Halle Saale Germany

5. Psycho‐Oncology Unit Azienda USL‐IRCCS di Reggio Emilia Reggio Emilia Italy

6. Clinical Trial Center‐Statistics Unit, SOC Infrastructure, Research and Statistics Azienda USL‐IRCCS di Reggio Emilia Reggio Emilia Italy

7. Department of History, College of Arts and Science USASK Saskatoon Saskatchewan Canada

8. Medicine Department Geneva University Geneva Switzerland

Abstract

Key Clinical MessageThis case study describes the feasibility and safety of psychedelic‐assisted therapy (PAT) as a home‐based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well. This case supports the feasibility and safety of PAT for patients with life‐threatening conditions in a home setting.AbstractPsychedelic‐assisted therapy (PAT), as it is practiced today, merges traditional psychotherapeutic techniques with the use of psychedelics such as LSD, psilocybin, or MDMA with the aim of unlocking deeper insights in patients and treating mental conditions that are resistant to other forms of therapy. The present case study describes the safety of PAT as a home‐based intervention for a patient with throat cancer experiencing significant existential distress. The patient tolerated the intervention well and was asked to report on measures of anxiety, depression, and distress related to his somatic condition. The observations provided by this clinical case report align with previous findings, suggesting that PAT can be safely applied to potentially provide relief from existential distress in patients with life‐threatening conditions. As this is a single‐case study, generalizations should be made cautiously. Moreover, placebo effects, expectancy effects, and the natural course of the disease may influence outcomes. Future research should consider controlled trials to ascertain the efficacy and safety of such interventions in diverse settings.

Publisher

Wiley

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