Determination of irinotecan, SN-38 and SN-38 glucuronide using HPLC/MS/MS: Application in a clinical pharmacokinetic and personalized medicine in colorectal cancer patients

Author:

Atasilp Chalirmporn12,Chansriwong Pichai3,Sirachainan Ekapob3,Reungwetwattana Thanyanan3,Puangpetch Apichaya12,Prommas Santirhat12,Sirilerttrakul Suwannee3,Rerkarmnuaychoke Budsaba4,Wongwaisayawan Sansanee5,Sukasem Chonlaphat12ORCID

Affiliation:

1. Division of Pharmacogenomics and Personalized Medicine; Department of Pathology; Faculty of Medicine Ramathibodi Hospital; Mahidol University; Bangkok Thailand

2. Laboratory for Pharmacogenomics, Clinical Pathology; Somdetch Phra Debharatana Medical Centre; Ramathibodi Hospital; Bangkok Thailand

3. Division of Medical Oncology; Department of Medicine; Faculty of Medicine Ramathibodi Hospital; Mahidol University; Bangkok Thailand

4. Division of Human Genetics Laboratory; Department of Pathology; Faculty of Medicine Ramathibodi Hospital; Mahidol University; Bangkok Thailand

5. Division of Anatomical Pathology; Department of Pathology; Faculty of Medicine Ramathibodi Hospital; Mahidol University; Bangkok Thailand

Funder

Ramathibodi Hospital Cancer Center, Bangkok, Thailand

Publisher

Wiley

Subject

Microbiology (medical),Biochemistry (medical),Medical Laboratory Technology,Clinical Biochemistry,Public Health, Environmental and Occupational Health,Hematology,Immunology and Allergy

Reference20 articles.

1. Atazanavir/ritonavir-based combination antiretroviral therapy for treatment of HIV-1 infection in adults;Achenbach;Future Virol,2011

2. Review of biomarkers in colorectal cancer;Newton;Colorectal Dis,2012

3. Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity;Di Paolo;Curr Drug Metab,2011

4. Phase I and pharmacokinetic trial of weekly CPT-11;Rothenberg;J Clin Oncol,1993

5. Clinical pharmacokinetics and metabolism of irinotecan (CPT-11);Mathijssen;Clin Cancer Res,2001

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