Novel method for assessing sinusoidal obstruction syndrome using four‐dimensional computed tomography

Abstract

AbstractIntroductionTo diagnose sinusoidal obstruction syndrome/veno‐occlusive disease (SOS/VOD), transabdominal ultrasonography is usually used to detect hemodynamic changes, but we tried to detect the changes using four‐dimensional computed tomography (4D‐CT). A 42‐year‐old Japanese woman was diagnosed with late‐onset SOS/VOD with transabdominal ultrasonography and was also assessed using 4D‐CT. Method We analyzed the portal vein (PV) contrast effect every 1.5 seconds and plotted the values of the contrast effect. With this graph, we analyzed three hemodynamic parameters.ResultWe found that these parameters correlated with the patient's status and indicated stasis due to sinusoid constriction.Conclusion4D‐CT may become a helpful tool to diagnose and follow up with SOS/VOD.