Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction

Author:

Bornschein Jan123ORCID,Wernisch Lorenz4,Secrier Maria5,Miremadi Ahmad6,Perner Juliane5,MacRae Shona1,O'Donovan Maria6,Newton Richard4,Menon Suraj5,Bower Lawrence5,Eldridge Matthew D.5,Devonshire Ginny5,Cheah Calvin1,Turkington Richard7,Hardwick Richard H.8,Selgrad Michael2,Venerito Marino2,Malfertheiner Peter2,Fitzgerald Rebecca C.1,Noorani Ayesha,Elliott Rachael Fels,Edwards Paul A.W.,Grehan Nicola,Nutzinger Barbara,Crawte Jason,Chettouh Hamza,Contino Gianmarco,Li Xiaodun,Gregson Eleanor,Zeki Sebastian,Rue Rachel,Malhotra Shalini,Tavaré Simon,Lynch Andy G.,Smith Mike L.,Davies Jim,Crichton Charles,Carroll Nick,Safranek Peter,Hindmarsh Andrew,Sujendran Vijayendran,Hayes Stephen J.,Ang Yeng,Preston Shaun R.,Oakes Sarah,Bagwan Izhar,Save Vicki,Skipworth Richard J.E.,Hupp Ted R.,Robert O'Neill J.,Tucker Olga,Beggs Andrew,Taniere Philippe,Puig Sonia,Underwood Timothy J.,Noble Fergus,Owsley Jack,Barr Hugh,Shepherd Neil,Old Oliver,Lagergren Jesper,Gossage James,Davies Andrew,Chang Fuju,Zylstra Janine,Goh Vicky,Ciccarelli Francesca D.,Sanders Grant,Berrisford Richard,Harden Catherine,Bunting David,Lewis Mike,Cheong Ed,Kumar Bhaskar,Parsons Simon L.,Soomro Irshad,Kaye Philip,Saunders John,Lovat Laurence,Haidry Rehan,Eneh Victor,Igali Laszlo,Scott Michael,Sothi Shamila,Suortamo Sari,Lishman Suzy,Hanna George B.,Peters Christopher J.,Grabowska Anna,

Affiliation:

1. MRC Cancer Unit, Hutchison/MRC Research CentreUniversity of Cambridge Cambridge United Kingdom

2. Department of Gastroenterology, Hepatology and Infectious DiseasesOtto‐von‐Guericke University Magdeburg Germany

3. Translational Gastroenterology UnitOxford University Hospitals Oxford United Kingdom

4. MRC Biostatistics UnitUniversity of Cambridge Cambridge United Kingdom

5. Cancer Research UK Cambridge InstituteUniversity of Cambridge Cambridge United Kingdom

6. Department of Histopathology, Addenbrooke's HospitalCambridge University Hospitals Cambridge United Kingdom

7. Department of OncologyQueen's University Northern Ireland United Kingdom

8. Department of Surgery, Addenbrooke's HospitalCambridge University Hospitals Cambridge United Kingdom

Funder

Cancer Research UK

Deutsche Forschungsgemeinschaft

National Institute for Health Research

Publisher

Wiley

Subject

Cancer Research,Oncology

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