Metabolism of methylstenbolone studied with human liver microsomes and the uPA+/+-SCID chimeric mouse model

Author:

Geldof Lore1,Lootens Leen1,Polet Michael1,Eichner Daniel2,Campbell Thane2,Nair Vinod2,Botrè Francesco3,Meuleman Philip4,Leroux-Roels Geert4,Deventer Koen1,Eenoo Peter Van1

Affiliation:

1. Doping Control Laboratory; Ghent University; Technologiepark 30 B Zwijnaarde B-9052 Belgium

2. Sports Medicine Research and Testing Laboratory; Arapeen drive 560 Salt Lake City UT 84108 USA

3. Laboratorio Antidoping; Federazione Medico Sportiva Italiana; Largo Giulio Onesti 1 Rome I-00197 Italy

4. Center for Vaccinology; Ghent University and Hospital; De Pintelaan 185 B-9000 Ghent Belgium

Funder

Partnership for Clean Competition

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference31 articles.

1. An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons;Brandon;Toxicology and Applied Pharmacology,2003

2. Detection of the methasterone and its metabolite in human urine by the gas chromatography/high resolution mass spectrometry (HRMS) method;Bylina;Methods and Objects of Chemical Analysis,2012

3. Detection of designer steroid methylstenbolone in ‘nutritional supplement’ using gas chromatography and tandem mass spectrometry: elucidation of its urinary metabolites;Cavalcanti;Steroids,2012

4. Schemes of metabolic patterns of anabolic androgenic steroids for the estimation of metabolites of designer steroids in human urine;Fragkaki;Journal of Steroid Biochemistry and Molecular Biology,2009

5. Identification of drostanolone and 17-methyldrostanolone metabolites produced by cryopreserved human hepatocytes;Gauthier;Steroids,2009

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