Comparative assessment of18F-Mefway as a serotonin 5-HT1Areceptor PET imaging agent across species: Rodents, nonhuman primates, and humans

Author:

Mukherjee Jogeshwar1,Bajwa Alisha K.1,Wooten Dustin W.2,Hillmer Ansel T.2,Pan Min-Liang1,Pandey Suresh K.1,Saigal Neil1,Christian Bradley T.2

Affiliation:

1. Preclinical Imaging; Department of Radiological Sciences; University of California; Irvine California 92697-5000

2. Department of Medical Physics and Waisman Center; University of Wisconsin; Madison Wisconsin 53705

Funder

National Institute of Aging

Publisher

Wiley

Subject

General Neuroscience

Reference68 articles.

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2. PET radiotracers for molecular imaging of serotonin 5-HT1A receptors;Billard;Curr Med Chem,2014

3. Hetergenous distribution of the serotonin 5-HT1A receptor mRNA in chemically identified neurons of the mouse rostral brainstem: implications for the role of serotonin in the regulation of wakefulness and REM sleep;Bonnavion;J Comp Neurol,2010

4. 3H-WAY-100635 for 5-HT1A receptor autoradiography in human brain: a comparison with 3H-8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia;Burnet;Neurochem Int,1997

5. Brain uptake of the acid metabolites of F-18-labeled WAY-100635 analogs;Carson;J Cereb Blood Flow Metab,2003

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