EGFL7 Is Expressed in Bone Microenvironment and Promotes Angiogenesis via ERK, STAT3, and Integrin Signaling Cascades

Author:

Chim Shek Man1,Kuek Vincent1,Chow Siu To1,Lim Bay Sie1,Tickner Jennifer1,Zhao Jinmin2,Chung Rosa3,Su Yu-Wen3,Zhang Ge4,Erber Wendy1,Xian Cory J.3,Rosen Vicki5,Xu Jiake12

Affiliation:

1. School of Pathology and Laboratory Medicine; University of Western Australia; Nedlands WA Australia

2. Research Centre for Regenerative Medicine; Department of Orthopaedic Surgery; The First Affiliated Hospital of Guangxi Medical University; Guangxi China

3. Sansom Institute for Health Research; School of Pharmacy and Medical Sciences; University of South Australia; Adelaide SA Australia

4. Institute for Advancing Translational Medicine in Bone and Joint Diseases; School of Chinese Medicine; Hong Kong Baptist University; Hong Kong

5. Developmental Biology; Harvard School of Dental Medicine; Boston Massachusetts

Funder

National Health and Medical Research Council of Australia

Western Australia Medical & Health Research Infrastructure Fund

National Natural Science Foundation of China (NSFC)

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference61 articles.

1. A physical mechanism for coupling bone resorption and formation in adult human bone;Andersen;Am J Pathol,2009

2. Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement;Arima;Development,2011

3. Osteoblast isolation from murine calvaria and long bones;Bakker;Methods Mol Biol,2012

4. New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression;Bauvois;Biochim Biophys Acta,2012

5. Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells;Behera;Carcinogenesis,2010

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