Developmental transcription factor NFIB is a putative target of oncofetal miRNAs and is associated with tumour aggressiveness in lung adenocarcinoma

Author:

Becker-Santos Daiana D1,Thu Kelsie L1,English John C2,Pikor Larissa A1,Martinez Victor D1,Zhang May1,Vucic Emily A1,Luk Margaret TY2,Carraro Anita1,Korbelik Jagoda1,Piga Daniela1,Lhomme Nicolas M1,Tsay Mike J3,Yee John4,MacAulay Calum E1,Lam Stephen1,Lockwood William W1,Robinson Wendy P5,Jurisica Igor36,Lam Wan L1

Affiliation:

1. Department of Integrative Oncology; British Columbia Cancer Research Centre; Vancouver British Columbia Canada

2. Department of Pathology; Vancouver General Hospital; Vancouver British Columbia Canada

3. Princess Margaret Cancer Centre; University Health Network; Toronto Ontario Canada

4. Department of Surgery; Vancouver General Hospital; Vancouver British Columbia Canada

5. Department of Medical Genetics; University of British Columbia; Vancouver British Columbia Canada

6. Departments of Medical Biophysics and Computer Science; University of Toronto; Toronto Ontario Canada

Funder

Canadian Institutes of Health Research

Canadian Cancer Society

Ontario Research Fund

Canada Foundation for Innovation

Canada Research Chair Program (CRC)

Vanier Canada Graduate Scholarships

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference45 articles.

1. Cancer as a complex developmental disorder - nineteenth Cornelius P. Rhoads Memorial Award Lecture;Dean;Cancer Res,1998

2. Genetic similarities between organogenesis and tumorigenesis of the lung;Powers;Cell Cycle,2008

3. Lung cancer: developmental networks gone awry?;Dong;Cancer Biol Ther,2009

4. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas;Bass;Nature Genet,2009

5. Characterizing the cancer genome in lung adenocarcinoma;Weir;Nature,2007

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