Model-directed engineering of “difficult-to-express” monoclonal antibody production by Chinese hamster ovary cells
Author:
Affiliation:
1. ChELSI Institute; Department of Chemical and Biological Engineering; University of Sheffield; Mappin Street Sheffield S1 3JD UK
2. Cell Sciences; BioPharmaceutical Development, MedImmune, Granta Park; Cambridge UK
Funder
Biotechnology and Biological Sciences Research Council
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Reference44 articles.
1. Recombinant protein production by large-scale transient gene expression in mammalian cells: State of the art and future perspectives;Baldi;Biotechnol Lett,2007
2. Differential efficiency of expression of humanized antibodies in transiently transfected mammalian cells;Bentley;Hybridoma,1998
3. Cyclosporine A-sensitive, Cyclophilin B-dependent endoplasmic reticulum-associated degradation;Bernasconi;PLoS ONE,2010
4. Selection methods for high-producing mammalian cell lines;Browne;Trends Biotechnol,2007
5. Impact of gene vector design on the control of recombinant monoclonal antibody production by Chinese hamster ovary cells;Davies;Biotechnol Prog,2011
Cited by 83 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Context-dependent genomic locus effects on antibody production in recombinant Chinese hamster ovary cells generated through random integration;Computational and Structural Biotechnology Journal;2024-12
2. RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1;Scientific Reports;2024-06-19
3. Nature as blueprint: Global phenotype engineering of CHO production cells based on a multi-omics comparison with plasma cells;Metabolic Engineering;2024-05
4. A systemic approach to identifying sequence frameworks that decrease mAb production in a transient Chinese hamster ovary cell expression system;Biotechnology Progress;2024-04-12
5. A deep‐well plate enabled automated high‐throughput cell line development platform;Biotechnology Progress;2024-02-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3