Determination of ethanamizuril, a novel triazine coccidiostat, in rat plasma by ultra‐performance liquid chromatography system‐tandem mass spectrometry and its application in a toxicological study

Author:

Wang Xiaoyang1,Zhao Juan1,Wei Shuya2,Wang Chunmei1,Zhang Lifang1,Wang Mi1,Liu Yingchun1,Fei Chenzhong1,Xue Feiqun1,Zhang Keyu1ORCID

Affiliation:

1. Key Laboratory of Veterinary Chemical Drugs and Pharmaceutics, Ministry of Agriculture and Rural AffairsShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences Shanghai China

2. School of Biological EngineeringWuhan Polytechnic Wuhan China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference14 articles.

1. Determination of diclazuril, toltrazuril and its two metabolites in poultry tissues and eggs by gel permeation chromatography‐ liquid chromatography‐ tandem mass spectrometry;Ai L.;Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences,2011

2. Pharmacokinetics of a novel triazine ethanamizuril in rats and broiler chickens;Cheng P.;Research in Veterinary Science,2018

3. Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens;Conway D. P.;Poultry Science,2001

4. Toxicokinetics and physiologically based toxicokinetics in toxicology and risk assessment;Dixit R.;Journal of Toxicology and Environmental Health. Part B, Critical Reviews,2003

5. FDA (US Food and Drug Administration). (2000a).Toxicological principles for the safety assessment of food ingredients. IV.C.3.A. Guidelines for short‐term toxicity studies with rodents 100–110.

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