Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer

Author:

Gargalionis Antonios N.1,Korkolopoulou Penelope2,Farmaki Elena1,Piperi Christina1,Dalagiorgou Georgia1,Adamopoulos Christos1,Levidou Georgia2,Saetta Angelica2,Fragkou Paraskevi2,Tsioli Panagiota2,Kiaris Hippokratis1,Zizi-Serbetzoglou Adamantia3,Karavokyros Ioannis4,Papavassiliou Kostas A.1,Tsavaris Nikolaos5,Patsouris Efstratios2,Basdra Efthimia K.1,Papavassiliou Athanasios G.1

Affiliation:

1. Department of Biological Chemistry; University of Athens Medical School; Athens Greece

2. First Department of Pathology; “Laikon” General Hospital, University of Athens Medical School; Athens Greece

3. Department of Pathology; “Tzaneio” General Hospital; Piraeus Greece

4. First Department of Surgery; “Laikon” General Hospital, University of Athens Medical School; Athens Greece

5. Department of Pathophysiology; Oncology Unit, “Laikon” General Hospital, University of Athens Medical School; Athens Greece

Funder

ELPEN Pharmaceutical Co. Inc. – Research & Experimental Center

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference45 articles.

1. What does physics have to do with cancer?;Michor;Nat Rev Cancer,2011

2. The physics of cancer: the role of physical interactions and mechanical forces in metastasis;Wirtz;Nat Rev Cancer,2011

3. Polycystins and partners: proposed role in mechanosensitivity;Retailleau;J Physiol,2014

4. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium;Cell,1994

5. Transmembrane domain analysis of polycystin-1, the product of the polycystic kidney disease-1 (PKD1) gene: evidence for 11 membrane-spanning domains;Nims;Biochemistry,2003

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