Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes

Author:

Chen Ying Ju1,Tsai Keh Sung2,Chan Ding Cheng3,Lan Kuo Cheng4,Chen Cheng Feng5,Yang Rong Sen6,Liu Shing Hwa17

Affiliation:

1. Institute of Toxicology; College of Medicine; National Taiwan University; No.1, Jen-Ai Road, Section 1 Taipei 10051 Taiwan

2. Department of Laboratory Medicine, College of Medicine; National Taiwan University & Hospital; Taipei Taiwan

3. Department of Geriatrics and Gerontology; National Taiwan University Hospital; Taipei Taiwan

4. Department of Emergency Medicine; National Defense Medical Center; Tri-Service General Hospital; Taipei Taiwan

5. Division of Plastic and Reconstructive Surgery; Sun Yat-Sen Cancer Center; Taipei Taiwan

6. Department of Orthopaedics, College of Medicine; National Taiwan University & Hospital; No. 7, Chung-Shan South Road Taipei Taiwan

7. Department of Medical Research; China Medical University Hospital, China Medical University; No. 91, Hsueh-Shih Road Taichung Taiwan

Publisher

Wiley

Subject

Orthopedics and Sports Medicine

Reference35 articles.

1. Osteoarthritis;Goldring;J Cell Physiol,2007

2. The role of cytokines in osteoarthritis pathophysiology;Fernandes;Biorheology,2002

3. Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1 β;Vincenti;Arthritis Res,2001

4. The role of cytokines in cartilage matrix degeneration in osteoarthritis;Goldring;Clin Orthop Relat Res,2004

5. Biochemical and metabolic abnormalities in normal and osteoarthritic human articular cartilage;Ryu;Arthritis Rheum,1984

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