FDA safety warning on the cardiac effects of lamotrigine: An advisory from the Ad Hoc ILAE/AES Task Force-Reference-Cited by-同舟云学术

FDA safety warning on the cardiac effects of lamotrigine: An advisory from the Ad Hoc ILAE/AES Task Force

Published:2021-02-25 Issue:1 Volume:6 Page:45-48
ISSN:2470-9239
Container-title:Epilepsia Open
language:en
Short-container-title:Epilepsia Open

Author:

French Jacqueline A.¹^ORCID,Perucca Emilio²^ORCID,Sander Josemir W.³⁴⁵^ORCID,Bergfeldt Lennart⁶⁷,Baulac Michel⁸,Auerbach David S.⁹^ORCID,Keezer Mark⁵¹⁰^ORCID,Thijs Roland D.³⁴⁵¹¹,Devinsky Orrin¹^ORCID,Vossler David G.¹²,Welty Timothy E.¹³

Affiliation:

1. Department of Neurology New York University Grossman School of Medicine and NYU Langone Health New York NY USA

2. Department of Internal Medicine and Therapeutics University of Pavia Pavia Italy

3. UCL Queen Square Institute of Neurology London UK

4. Chalfont Centre for Epilepsy Chalfont St Peter UK

5. Stichting Epilepsie Instellingen Nederland (SEIN) Heemstede The Netherlands

6. Department of Molecular & Clinical Medicine Institute of Medicine Sahlgrenska Academy, University of Gothenburg Gothenburg Sweden

7. Department of Cardiology Sahlgrenska University Hospital Gothenburg Sweden

8. Department of Neurology, Salpetrière University Hospital & ICM Sorbonne Université Paris France

9. Department of Pharmacology SUNY Upstate Medical University Syracuse NY USA

10. Department of Neurosciences School of Public Health of the Université de Montréal Montreal QC Canada

11. Department of Neurology Leiden University Medical Centre Leiden The Netherlands

12. University of Washington Seattle WA USA

13. College of Pharmacy and Health Sciences Drake University Des Moines IA USA

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/epi4.12475

Reference7 articles.

1. Lamictal.Full prescribing information (last revised October 2020).GlaxoSmithKline Research Triangle Park NC 27709 USA. Available fromhttps://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Lamictal/pdf/LAMICTAL‐PI‐MG.PDF(last accessed January 4 2021)

2. Cardiac function and antiepileptic drug treatment in the elderly: A comparison between lamotrigine and sustained-release carbamazepine

3. Signal-averaged and standard electrocardiography in patients with newly diagnosed epilepsy

4. On the relationship between block of the cardiac Na+channel and drug-induced prolongation of the QRS complex

5. Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects

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