Affiliation:
1. Key Laboratory of Urban Agriculture (North China) Ministry of Agriculture and Rural Affairs of the People's Republic of China, Beijing University of Agriculture Beijing China
2. Weihai Ocean Vocational College Weihai China
3. Shandong Dyne Marine Biopharmaceutical Co., Ltd. Weihai China
Abstract
AbstractA convenient and efficient method is developed for the synthesis of 1,2,3,4,6‐pentasubstituted piperidines via a three‐component, one‐pot domino reaction of β‐ketoesters, aromatic aldehydes, and aromatic amines in the presence of a catalytic amount of saccharin in methanol at 40°C. The desired piperidines could be easily collected through simple filtration with excellent diastereoselectivities.
Funder
Beijing Municipal Natural Science Foundation
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献