Epimerization in peptide thioester condensation

Author:

Teruya Kenta12,Tanaka Takeyuki3,Kawakami Toru1,Akaji Kenichi14,Aimoto Saburo1

Affiliation:

1. Institute for Protein Research; Osaka University; 3-2, Yamadaoka Suita Osaka 565-0871 Japan

2. Department of Chemistry, Graduate School of Medical Science; Kyoto Prefectural University of Medicine; Kita-ku Kyoto 603-8334 Japan

3. Department of Life Science, Graduate School of Science and Technology; Kobe University; 1-1 Rokkodai-cho Nada-ku Kobe 657-8501 Japan

4. Department of Medicinal Chemistry; Kyoto Pharmaceutical University; Yamashina-ku Kyoto 607-8412 Japan

Publisher

Wiley

Subject

Organic Chemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry,Structural Biology

Reference39 articles.

1. Polypeptide synthesis by the thioester method;Aimoto;Biopolymers (Peptide Sci.),1999

2. Synthesis of native protein by chemical ligation;Dawson;Annu. Rev. Biochem.,2000

3. Polypeptide synthesis using the S-alkyl thioester of a partially protected peptide segment. Synthesis of the DNA binding domain of c-Myb protein (142-193)-NH2;Hojo;Bull. Chem. Soc. Jpn.,1991

4. Synthesis of Proteins by native chemical ligation;Dawson;Science,1994

5. Emerging methods in amide- and peptide-bond formation;Bode;Curr. Opin. Drug Discov. Devel.,2006

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