Influence of agonist induced internalization on [3H]Ro15-4513 binding-an application to imaging fluctuations in endogenous GABA with positron emission tomography

Author:

Quelch Darren1,De Santis Vittorio2,Strege Annette3,Myers James1,Wells Lisa2,Nutt David1,Lingford-Hughes Anne1,Parker Christine4,Tyacke Robin1

Affiliation:

1. Centre for Neuropsychopharmacology; Division of Brain Sciences; Imperial College; London UK

2. Imanova Centro for Imaging Sciences; London UK

3. Life Science Department; Imperial College; London UK

4. Global Imaging Unit; GlaxoSmithKline; Stevenage UK

Funder

Biotechnology and Biological Sciences Research Council

GlaxoSmithKline

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference53 articles.

1. Do we still believe in the dopamine hypothesis? New data bring new evidence;Abi-Dargham;Int J Neuropsychopharmacol,2004

2. Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site;Borden;Receptors Channels,1994

3. Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes;Bowery;Br J Pharmacol,1983

4. Regulation of intracellular calcium in squid axons;Brinley;Federation Proc,1980

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