Medium optimization and subsequent fermentative regulation enabled the scaled‐up production of anti‐tuberculosis drug leads ilamycin‐E1/E2-Reference-Cited by-同舟云学术

Medium optimization and subsequent fermentative regulation enabled the scaled‐up production of anti‐tuberculosis drug leads ilamycin‐E1/E2

Published:2022-02-10 Issue:4 Volume:17 Page:2100427
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnology Journal

Author:

Fan Zhiying¹,Tong Nian¹,Zhuang Zhoukang¹,Ma Cheng²,Ma Junying³,Ju Jianhua³,Duan Yanwen¹²⁴,Zhu Xiangcheng¹²⁴^ORCID

Affiliation:

1. Xiangya International Academy of Translational Medicine Central South University Changsha Hunan China

2. National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery Changsha Hunan China

3. CAS Key Laboratory of Tropical Marine Bio‐resources and Ecology Guangdong Key Laboratory of Marine Materia Medica RNAM Center for Marine Microbiology South China Sea Institute of Oceanology Chinese Academy of Sciences Guangzhou China

4. Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discovery Changsha China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202100427

Reference18 articles.

1. What is Tuberculosis (TB)?

2. WHO global progress report on tuberculosis elimination

3. Recent updates on drug resistance in Mycobacterium tuberculosis

4. Antibiotic resistance mechanisms in M. tuberculosis: an update

5. Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

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