The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity

Author:

Ptacek Jakub12,Nedvedova Jana1,Navratil Michal23,Havlinova Barbora1,Konvalinka Jan23,Barinka Cyril1ORCID

Affiliation:

1. Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV; Prumyslova 595, 25250 Vestec Czech Republic

2. Department of Biochemistry; Charles University; Prague 2 Czech Republic

3. Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences; 16610 Prague 6 Czech Republic

Funder

Akademie Věd České Republiky

European Regional Development Fund

Grantová Agentura České Republiky

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference34 articles.

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2. Announcing the worldwide Protein Data Bank;Berman;Nat Struct Biol,2003

3. The Biological Chemistry of the Elements - the Inorganic-Chemistry of Life - Dasilva JJR;Martin;Williams RJP. Nature,1991

4. Metal ions in biological catalysis: from enzyme databases to general principles;Andreini;J Biol Inorg Chem,2008

5. Metalloproteomes: a Bioinformatic Approach;Andreini;Acc Chem Res,2009

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