Evaluation of options for harvest of a recombinantE. Colifermentation producing a domain antibody using ultra scale-down techniques and pilot-scale verification
Author:
Affiliation:
1. Dept. of Biochemical Engineering; The Advanced Centre for Biochemical Engineering, UCL; Gower St London WC1E 6BT
2. Biopharm Process Research, BioPharm R&D, GlaxoSmithKline, R&D; Stevenage SG1 2NY
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2220/fullpdf
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3. Unstable proteins: how to subject them to chromatographic separations for purification procedures;Kaufmann;J Chromatogr B Biomed Sci Appl.,1997
4. Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins;Mamat;Microb Cell Fact.,2015
5. Selective leakage of Host-Cell Proteins during high-cell-density cultivation of recombinant and non-recombinant Escherichia coli;Rinas;Biotechnol Prog.,2004
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