Fat Metaplasia and Backfill Are Key Intermediaries in the Development of Sacroiliac Joint Ankylosis in Patients With Ankylosing Spondylitis

Author:

Maksymowych Walter P.1,Wichuk Stephanie1,Chiowchanwisawakit Praveena2,Lambert Robert G.1,Pedersen Susanne J.34

Affiliation:

1. University of Alberta, Edmonton; Alberta Canada

2. Siriraj Hospital and Mahidol University; Bangkok Thailand

3. University of Alberta; Edmonton, Alberta Canada

4. University of Copenhagen; Copenhagen Denmark

Funder

Spondyloarthritis Research Consortium of Canada

Danish Council for Independent Research in the Medical Sciences

Alberta Innovates Health Solutions

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference35 articles.

1. Advances and challenges in spondyloarthritis imaging for diagnosis and assessment of disease;Weber;Curr Rheumatol Rep,2013

2. Structural lesions detected by magnetic resonance imaging in the spine of patients with spondyloarthritis: definitions, assessment system, and reference image set;Ostergaard;J Rheumatol,2009

3. Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group;Rudwaleit;Ann Rheum Dis,2009

4. Descriptions of spinal MRI lesions and definition of a positive MRI of the spine in axial SpA;Hermann;Ann Rheum Dis,2012

5. Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis;Chiowchanwisawakit;Arthritis Rheum,2011

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