Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate-Reference-Cited by-同舟云学术

Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate

Published:2018-02-02 Issue:4 Volume:104 Page:749-756
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Ali Izna¹,Slizgi Jason R.¹,Kaullen Josh D.¹,Ivanovic Marija²,Niemi Mikko³⁴,Stewart Paul W.⁵,Barritt Alfred S.⁶,Brouwer Kim L.R.¹

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics; University of North Carolina (UNC) Eshelman School of Pharmacy, UNC at Chapel Hill (UNC-CH); Chapel Hill North Carolina USA

2. Department of Radiology; UNC Health Care, UNC-CH; Chapel Hill North Carolina USA

3. Department of Clinical Pharmacology; University of Helsinki; Helsinki Finland

4. HUSLAB, Helsinki University Central Hospital; Helsinki Finland

5. Department of Biostatistics; UNC Gillings School of Global Public Health, UNC-CH; Chapel Hill North Carolina USA

6. Division of Gastroenterology and Hepatology; UNC School of Medicine, UNC-CH; Chapel Hill North Carolina USA

Funder

National Institute of General Medical Sciences

National Institutes of Health

Clinical Pharmacokinetics/Pharmacodynamics fellowship

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.997/fullpdf

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