Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review

Author:

Tajmohammadi Atefeh1,Razavi Bibi Marjan23,Hosseinzadeh Hossein43ORCID

Affiliation:

1. School of Pharmacy; Mashhad University of Medical Sciences; Mashhad Iran

2. Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute; Mashhad University of Medical Sciences; Mashhad Iran

3. Department of Pharmacodynamics and Toxicology, School of Pharmacy; Mashhad University of Medical Sciences; Mashhad Iran

4. Pharmaceutical Research Center, Pharmaceutical Technology Institute; Mashhad University of Medical Sciences; Mashhad Iran

Publisher

Wiley

Subject

Pharmacology

Reference69 articles.

1. Silybin attenuates cardiac hypertrophy and fibrosis through blocking EGFR-dependent signaling;Ai;Journal of Cellular Biochemistry,2010

2. Grapes (Vitis vinifera) as a potential candidate for the therapy of the metabolic syndrome;Akaberi;Phytotherapy Research,2016

3. Modulation of calcium signaling of angiotensin AT1, endothelin ETA, and ETB receptors by silibinin, quercetin, crocin, diallyl sulfides, and ginsenoside Rb1;Bahem;Planta Medica,2015

4. Silybum marianum: Beyond hepatoprotection;Bahmani;J Evid Based Complementary Altern Med,2015

5. Beneficial effects of silibinin against the progression of metabolic syndrome, increased oxidative stress, and liver steatosis in Psammomys obesus, a relevant animal model of human obesity and diabetes;Bouderba;Journal of Diabetes,2014

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