SRM targeted proteomics in search for biomarkers of HCV-induced progression of fibrosis to cirrhosis in HALT-C patients

Author:

Qin Shizhen1,Zhou Yong1,Lok Anna S.2,Tsodikov Alex3,Yan Xiaowei1,Gray Li1,Yuan Min1,Moritz Robert L.1,Galas David1,Omenn Gilbert S.14,Hood Leroy1

Affiliation:

1. Institute for Systems Biology; Seattle Washington USA

2. Department of Internal Medicine; University of Michigan; Ann Arbor Michigan USA

3. Department of Biostatistics; University of Michigan; Ann Arbor Michigan USA

4. Department of Internal Medicine and Center for Computational Medicine and Bioinformatics; University of Michigan; Ann Arbor Michigan USA

Funder

Luxembourg Centre for Systems Biomedicine and the University of Luxembourg for Leroy Hood

National Institutes of Health-National Human Genome Research Institute

NIH National Center for Integrative Biomedical Informatics

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference32 articles.

1. Diagnosis, management, and treatment of hepatitis C: an update;Ghany;Hepatology,2009

2. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection;Regev;Am. J. Gastroenterol,2002

3. Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience;Munteanu;J. Gastrointestin. Liver Dis,2008

4. Impact of disease severity on outcome of antiviral therapy for chronic hepatitis C: lessons from the HALT-C trial;Everson;Hepatology,2006

5. AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection;Sheth;Am. J. Gastroenterol,1998

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