Affiliation:
1. Department of Clinical Laboratory Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
2. Hubei Key Laboratory of Regenerative Medicine and Multi‐disciplinary Translational Research Hubei Provincial Engineering Research Center of Clinical Laboratory and Active Health Smart Equipment Research Center for Tissue Engineering and Regenerative Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
3. Department of Gastrointestinal Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
Abstract
AbstractSericin, a protein derived from silkworm cocoons, is considered a waste product derived from the silk industry for thousands of years due to a lack of understanding of its properties. However, in recent decades, a range of exciting properties of sericin are studied and uncovered, including cytocompatibility, low‐immunogenicity, photo‐luminescence, antioxidant properties, as well as cell‐function regulating activities. These properties make sericin‐based biomaterials promising candidates for biomedical applications. This review summarizes the properties and bioactivities of silk sericin and highlights the latest developments in sericin in tissue engineering and regenerative medicine. Furthermore, the extended application of sericin in developing flexible electronic devices and 3D bioprinting is also discussed. It is believed that sericin‐based biomaterials have great potential of being developed into novel tissue engineering products and smart implantable devices for various medical applications toward improving clinical outcomes.
Funder
National Key Research and Development Program of China
Cited by
4 articles.
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