Roadmap for Clinical Translation of Mobile Microrobotics

Author:

Bozuyuk Ugur1,Wrede Paul12,Yildiz Erdost1ORCID,Sitti Metin13ORCID

Affiliation:

1. Physical Intelligence Department Max Planck Institute for Intelligent Systems 70569 Stuttgart Germany

2. Institute for Biomedical Engineering ETH Zurich Zurich 8093 Switzerland

3. School of Medicine and College of Engineering Koc University Istanbul 34450 Turkey

Abstract

AbstractMedical microrobotics is an emerging field to revolutionize clinical applications in diagnostics and therapeutics of various diseases. On the other hand, the mobile microrobotics field has important obstacles to pass before clinical translation. This article focuses on these challenges and provides a roadmap of medical microrobots to enable their clinical use. From the concept of a “magic bullet” to the physicochemical interactions of microrobots in complex biological environments in medical applications, there are several translational steps to consider. Clinical translation of mobile microrobots is only possible with a close collaboration between clinical experts and microrobotics researchers to address the technical challenges in microfabrication, safety, and imaging. The clinical application potential can be materialized by designing microrobots that can solve the current main challenges, such as actuation limitations, material stability, and imaging constraints. The strengths and weaknesses of the current progress in the microrobotics field are discussed and a roadmap for their clinical applications in the near future is outlined.

Funder

Eidgenössische Technische Hochschule Zürich

Max-Planck-Gesellschaft

H2020 Marie Skłodowska-Curie Actions

European Research Council

Publisher

Wiley

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Light-Driven Microrobots for Targeted Drug Delivery;ACS Biomaterials Science & Engineering;2024-08-15

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