Smart process development: Application of machine‐learning and integrated process modeling for inclusion body purification processes
Author:
Affiliation:
1. Process Science Boehringer‐Ingelheim RCV GmbH & CoKG Wien Austria
2. BI X GmbH Ingelheim Germany
3. Aramco Dhahran Saudi Arabia
4. Takeda Pharmaceuticals Vienna Austria
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3249
Reference27 articles.
1. ICH.International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use ICH Harmonized Tripartite Guideline: Pharmaceutical Development Q8(R2);2009.
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3. Design strategies for integrated protein purification processes: challenges, progress and outlook
4. Model-based integrated optimization and evaluation of a multi-step ion exchange chromatography
5. High-throughput micro-scale cultivations and chromatography modeling: Powerful tools for integrated process development
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