Syntheses of Tetrahydrobenzodiazepines via SN2-Type Ring-Opening of Activated Aziridines with 2-Bromobenzylamine Followed by Copper-Powder-Mediated C−N Bond Formation
Author:
Affiliation:
1. Department of Chemistry; Indian Institute of Technology Kanpur; Kanpur 208016, Uttar Pradesh India
Funder
IIT-Kanpur
CSIR, India
UGC, India
Publisher
Wiley
Subject
Organic Chemistry
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3. Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity
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