Metabolic chiral inversion of ibuprofen in isolated rat hepatocytes

Author:

Müller Sylvia,Mayer Joachim M.,Etter Jean-Claude,Testa Bernard

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference19 articles.

1. The metabolic inversion of 2-arylpropionic acids, a novel route with pharmacological consequences;Hutt;J. Pharm. Pharmacol.,1983

2. The stereoselective uptake of ibuprofen enantiomers into adipose tissue;Williams;Biochem. Pharmacol.,1986

3. Inhibition of mitochondrional β-oxydation in fatty acids by pirprofen. Role in microvesicular steatois due to this anti-inflammatory drug;Geneve;J. Pharmacol. Exp. Ther.,1987

4. Metabolic chiral inversion of anti-inflammatory 2-arylpropionates: Lack of reaction in liver homogenates, and study of methine proton acidity;Mayer;Xenobiotica,1988

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