Comparison of cord blood pro‐BNP levels in newborns of SARS‐COV‐2‐positive and ‐negative women, and its association with adverse perinatal outcomes

Abstract

AbstractObjectiveTo compare umbilical cord blood pro‐B‐type natriuretic peptide (BNP) levels in newborns of severe acute respiratory syndrome coronavirus 2 (SARS‐COV‐2) positive pregnancies to those of SARS‐COV‐2 negative pregnancies.MethodsProspectively cord blood samples from newborns of 42 SARS‐COV‐2 positive women, and 42 negative pregnant were collected at birth and analyzed for pro‐BNP levels.ResultsThe mean cord blood pro‐BNP level was significantly higher in newborns of SARS‐COV‐2 positive women than in controls. Furthermore, the pro‐BNP level was an independent predictor of NİCU admission in both SARS‐COV‐2 positive and control patients.ConclusionCord blood pro‐BNP level may be a parameter that can predict the under‐stress fetus and adverse perinatal outcomes especially, in cases where placental involvement is present as in SARS‐COV‐2 infection.