Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug-Reference-Cited by-同舟云学术

Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug

Published:2014-04-22 Issue:3 Volume:2 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Klieber Sylvie¹,Arabeyre‐Fabre Catherine¹,Moliner Patricia¹,Marti Eric¹,Mandray Martine¹,Ngo Robert¹,Ollier Céline¹,Brun Priscilla¹,Fabre Gérard¹

Affiliation:

1. SANOFI‐AVENTIS Recherche & Development Disposition Safety and Animal Research Scientific Core Platform Drug Disposition Domain 371 Rue du Professeur Joseph Blayac 34184 Montpellier Cedex 4 France

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.44

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3. Inducibility and expression of class IA and IIIA cytochromes P450 in primary cultures of adult human hepatocytes;Daujat M;Biochem Pharmacol (Life Sci Adv),1990

4. A simple method for screening Monoamine Oxidase (MAO) inhibitory drugs for type preference

5. Characterization of midazolam metabolism using human hepatic musomal fractions and hepatocytes in suspension obtained by perfusing whole human livers

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