A comparative evaluation of models to predict human intestinal metabolism from nonclinical data-Reference-Cited by-同舟云学术

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A comparative evaluation of models to predict human intestinal metabolism from nonclinical data

Published:2017-04 Issue:3 Volume:38 Page:163-186
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Yau Estelle¹^ORCID,Petersson Carl¹,Dolgos Hugues¹,Peters Sheila Annie¹

Affiliation:

1. Global Early Development/Quantitative Pharmacology and Drug Disposition (QPD), Merck; Darmstadt Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference58 articles.

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2. The right compound in the right assay at the right time: an integrated discovery DMPK strategy;Ballard;Drug Metab Rev,2012

3. Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination;Varma;J Med Chem,2010

4. The human intestinal cytochrome P450 ‘pie’;Paine;Drug Metab Dispos Biol Fate Chem,2006

5. Prediction of human pharmacokinetics - gut-wall metabolism;Fagerholm;J Pharm Pharmacol,2007

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