Affiliation:
1. Department of Diagnostic and Interventional Radiology University Hospital Würzburg Würzburg Germany
2. Comprehensive Heart Failure Center University Hospital Würzburg Würzburg Germany
3. Bruker BioSpin GmbH & Co. KG Ettlingen Germany
4. Nuffield Department of Clinical Neuroscience University of Oxford Oxford UK
5. Faculty of Industrial Design Engineering Delft University of Technology Delft The Netherlands
6. Leeds Institute of Cardiovascular and Metabolic Medicine University of Leeds Leeds UK
Abstract
AbstractThis study aimed to examine different trajectory correction methods for spiral imaging on a preclinical scanner with high‐performance gradients with respect to image quality in a phantom and in vivo. The gold standard method of measuring the trajectories in a separate experiment is compared to an isotropic delay‐correction, a correction using the gradient system transfer function (GSTF), and a combination of the two. Three different spiral trajectories, with 96, 16, and three interleaves, are considered. The best image quality is consistently achieved when determining the trajectory in a separate phantom measurement. However, especially for the spiral with 96 interleaves, the other correction methods lead to almost comparable results. Remaining imperfections in the corrected gradient waveforms and trajectories are attributed to asymmetrically occurring undulations in the actual, generated gradients, suggesting that the underlying assumption of linearity is violated. In conclusion, images of sufficient quality can be acquired on preclinical small‐animal scanners using spiral k‐space trajectories without the need to carry out separate trajectory measurements each time. Depending on the trajectory, a simple isotropic delay‐correction or a GSTF‐based correction can provide images of similar quality.
Funder
Wellcome Trust DBT India Alliance
British Heart Foundation
Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg