Assessment of tandem mass spectrometry and high-resolution mass spectrometry for the analysis of bupivacaine in plasma

Author:

Gaudette Fleur1,Benito Javier2,Steagall Paulo3,Beaudry Francis13

Affiliation:

1. Centre de Recherche du Centre Hospitalier Universitaire de l'Université de Montréal; Montréal Québec Canada (CRCHUM)

2. Département de Sciences Cliniques, Faculté de Médecine Vétérinaire; Université de Montréal; Saint-Hyacinthe Québec Canada

3. Groupe de Recherche en Pharmacologie Animal du Québec, Département de Biomédecine Vétérinaire, Faculté de Médecine Vétérinaire; Université de Montréal; Saint-Hyacinthe Québec Canada

Funder

National Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference24 articles.

1. High-throughput quantitative and qualitative analysis of microsomal incubations by cocktail analysis with an ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometer system;Backfisch;Bioanalysis,2014

2. Statistical evaluation of linearity and non-linearity of LC-MS/MS quantitation analysis;Beaudry;Pharmaceutical Science,1999

3. Pharmacokinetics of bupivacaine after intraperitoneal administration in cats;Benito;Veterinary Anaesthesia and Analgesia,2015

4. Statistical issues in quality control of proteomic analyses: good experimental design and planning;Cairns;Proteomics,2011

5. CDER and CVM Guidance for Industry. Bioanalytical Method Validation 2001 http://www.fda.gov/cder/

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