MAP3K11/GDF15 axis is a critical driver of cancer cachexia

Author:

Lerner Lorena1ORCID,Tao Julie1,Liu Qing1,Nicoletti Richard1,Feng Bin1,Krieger Brian1,Mazsa Elizabeth1,Siddiquee Zakir1,Wang Ruoji1,Huang Lucia12,Shen Luhua13,Lin Jie14,Vigano Antonio5,Chiu M. Isabel16,Weng Zhigang1,Winston William17,Weiler Solly1,Gyuris Jeno1

Affiliation:

1. AVEO Oncology; One Broadway 14th Floor Cambridge MA 02142 USA

2. Novartis Institutes for BioMedical Research; 211 Massachusetts Ave. Cambridge MA 02139 USA

3. Moderna Therapeutics; 200 Technology Square Cambridge MA 02139 USA

4. Stealth Peptides Inc.; 275 Grove Street, Ste.3-107 Newton MA 02466 USA

5. McGill Nutrition and Performance Laboratory; (MNUPAL); McGill University Health Centre (MUHC); Montreal Canada

6. Enumeral Biomedical Corp; One Kendall Square Building 400 Cambridge MA 02139 USA

7. POTENZA Therapeutics; 700 Main Street Cambridge MA 02139 USA

Publisher

Wiley

Subject

Physiology (medical),Orthopedics and Sports Medicine

Reference46 articles.

1. Cachexia as a major underestimated and unmet medical need: facts and numbers;Haehling;J Cachexia Sarcopenia Muscle,2010

2. Cancer anorexia-cachexia syndrome;Muliawati;Acta Med Indones,2012

3. Cancer cachexia: mechanisms and clinical implications;Donohoe;Gastroenterology research and practice,2011

4. Cachexia: a problem of energetic inefficiency;Argiles;J Cachexia Sarcopenia Muscle,2014

5. The energy balance in cancer cachexia revisited;Vos-Geelen;Curr Opin Clin Nutr Metab Care,2014

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