Anorectic efficacy and safety of the diethylpropion-topiramate combination in rats

Author:

Cortés-Moreno Gabriela Y.1,Roa-Coria José E.1,Zúñiga-Romero Ángel1,Huerta-Cruz Juan C.1,Lara-Padilla Eleazar1,del Valle-Laisequilla Cecilia F.2,Rocha-González Héctor I.1,Reyes-García Juan G.1ORCID

Affiliation:

1. Sección de Estudios de Posgrado e Investigación Escuela Superior de Medicina; Instituto Politécnico Nacional. Plan de San Luis y Díaz Mirón s/n, Col. Casco de Santo Tomas, Miguel Hidalgo; Ciudad de México 11340 Mexico

2. Laboratorios Medix S.A. de C.V. Calzada del Hueso 39, Ejido, Viejo, 04650, Col. de Santa, Úrsula Coapa, Coyoacán; Ciudad de México Mexico

Funder

JGR-G

HIR-G

Laboratorios Medix S.A. de C.V.

Publisher

Wiley

Subject

Drug Discovery

Reference42 articles.

1. Topiramate induces weight loss and improves insulin sensitivity in dietary obese rats: Comparison to sibutramine;Abo-Elmatty;European Review for Medical and Pharmacological Sciences,2011

2. Topiramate inhibits trigeminovascular activation: An intravital microscopy study;Akerman;British Journal of Pharmacology,2005

3. Combination phentermine and topiramate extended release in the management of obesity;Alfaris;Expert Opinion Pharmacotherapy,2015

4. Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP);Allison;Obesity,2012

5. Further evidence of the inhibitory role of perifornical hypothalamic beta-adrenergic receptors in the feeding behaviour of hungry rats;Bendotti;Life Sciences,1986

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